Description
MITOPRIME BLEND
For Research Use Only | Not for Human or Veterinary Use
Description:
MitoPrime combines three compounds studied together for their converging action on NAD⁺ availability and mitochondrial metabolism. NAD⁺ is the dinucleotide coenzyme itself, central to redox reactions and to the sirtuin family of NAD⁺-dependent deacetylases. MOTS-c is a mitochondria-derived peptide encoded in the 12S rRNA that signals to the nucleus and is investigated in AMPK-linked metabolic regulation. 5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide and diverts it from the NAD⁺ salvage pathway. The three are investigated as a stack that supplies the coenzyme, signals through a mitochondrial peptide, and reduces salvage-pathway loss in preclinical research models.
Scientific Specifications:
- Blend Components: NAD⁺ + MOTS-c + 5-Amino-1MQ
- Type: Three-Component Blend (Dinucleotide Coenzyme + Mitochondria-Derived Peptide + NNMT Inhibitor)
- NAD⁺: Nicotinamide Adenine Dinucleotide · C₂₁H₂₇N₇O₁₄P₂ · 663.43 g/mol · CAS 53-84-9 · PubChem 5892
- MOTS-c: Mitochondrial ORF of the 12S rRNA Type-c · MRWQEMGYIFYPRKLR (16aa) · C₁₀₁H₁₅₂N₂₈O₂₂S₂ · ~2174.6 g/mol · CAS 1627580-64-6 · PubChem 121231475
- 5-Amino-1MQ: 5-amino-1-methylquinolinium · C₁₀H₁₁N₂ · 159.21 g/mol · CAS 42464-96-0 · PubChem 950107
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
The MitoPrime Blend is commonly studied for its potential effects on:
- NAD⁺ pool availability and the nicotinamide salvage pathway
- Sirtuin (SIRT1 to SIRT7) activation and NAD⁺-dependent deacetylase activity
- Mitochondrial oxidative phosphorylation and electron transport chain function
- AMPK-linked metabolic signaling and mitochondrial-to-nuclear communication (MOTS-c)
- NNMT inhibition and methyl-group handling in adipose and muscle research models
- Cellular energy metabolism, substrate utilization and metabolic flexibility
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
