Description
ARA-290
For Research Use Only | Not for Human or Veterinary Use
Description:
ARA-290, also known as Cibinetide, is a synthetic 11-amino acid peptide derived from a tissue-protective region of erythropoietin (EPO). It was developed to retain the cytoprotective and anti-inflammatory properties of EPO without stimulating erythropoiesis or hematopoietic activity. ARA-290 selectively activates the innate repair receptor (IRR), a heterodimer composed of EPOR and CD131, which has been associated with cellular protection, inflammation modulation, and nerve regeneration in controlled research models. It is commonly explored in experimental settings focused on inflammatory signaling, neuropathic mechanisms, and tissue stress response pathways.
Scientific Specifications:
- Compound Name: ARA-290 (Cibinetide)
- Type: Synthetic Peptide (EPO-derived, non-hematopoietic)
- Sequence: pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
- Sequence (Short): ZEQLERALNSS
- Molecular Formula: C₅₁H₈₄N₁₆O₂₁
- Molecular Weight: ~1257.3 g/mol
- CAS Number: 1208243-50-8
- PubChem CID: 91810664
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
ARA-290 is commonly studied for its potential effects on:
- Tissue-protective signaling via innate repair receptor (IRR) activation
- Modulation of inflammatory cytokine pathways
- Neural protection and nerve regeneration models
- Neuropathic and sensory-related mechanisms
- Cellular recovery and stress response research
- EPOR/CD131 receptor-mediated signaling pathways
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance. All sales are final.
