Description
FOXO4-DRI
For Research Use Only | Not for Human or Veterinary Use
Description:
FOXO4-DRI is a synthetic D-retro-inverso peptide investigated in research for its senolytic properties. This compound selectively targets senescent cells by disrupting the FOXO4-p53 interaction, which leads to targeted apoptosis of senescent cells. Senescent cells are considered key drivers of aging and age-related tissue dysfunction. FOXO4-DRI represents a novel approach to cellular senescence clearance and has been studied in experimental models of aging, tissue regeneration, and metabolic dysfunction.
Scientific Specifications:
- Compound Name: FOXO4-DRI (FOXO4 D-Retro-Inverso)
- Type: D-Retro-Inverso Senolytic Peptide
- Molecular Formula: C₂₂₈H₃₈₈N₈₆O₆₄
- Molecular Weight: ~5358.05 g/mol
- CAS Number: 2460055-10-9
- Form: Lyophilized powder
Research Context:
FOXO4-DRI is commonly studied for its potential effects on:
- Senolytic activity and selective senescent cell elimination
- Cellular senescence clearance and FOXO4-p53 interaction disruption
- p53-mediated apoptosis in senescent cell populations
- Age-related tissue dysfunction and regenerative capacity models
- SASP (senescence-associated secretory phenotype) reduction and inflammatory marker modulation
- Aging research models and lifespan/healthspan parameter assessment
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
