Description
PT-141
For Research Use Only | Not for Human or Veterinary Use
Description:
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide melanocortin receptor agonist derived from the metabolite of Melanotan II. In preclinical laboratory research, PT-141 is investigated for its selective activity at melanocortin receptors MC3R and MC4R, distinguishing it from broader melanocortin agonists. The peptide’s cyclic lactam structure and C-terminal free acid (rather than amide) differentiate it structurally from its parent compound Melanotan II. PT-141 serves as a key pharmacological tool for studying melanocortin receptor-mediated central nervous system pathways, particularly those involved in sexual function, arousal signaling, and hypothalamic neuroendocrine regulation.
Scientific Specifications:
- Peptide Name: PT-141 (Bremelanotide)
- Type: Synthetic Cyclic Heptapeptide (Melanocortin Receptor Agonist)
- Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Molecular Formula: C₅₀H₆₈N₁₄O₁₀
- Molecular Weight: 1025.18 g/mol
- CAS Number: 189691-06-3
- PubChem CID: 9941379
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
PT-141 is commonly studied for its potential effects on:
- MC3R and MC4R selective agonism and melanocortin receptor binding pharmacology
- Central nervous system-mediated sexual function and arousal signaling pathways
- Hypothalamic melanocortin circuit activation and neuroendocrine downstream effects
- Structure-activity relationships between cyclic melanocortin peptide analogues
- Comparative pharmacology with non-selective melanocortin agonists (e.g., Melanotan II)
- Dopaminergic pathway interactions and reward-related neural circuit modulation
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
What is PT-141?+
PT-141 is a synthetic peptide (a cyclic heptapeptide). ezPeps supplies it as a laboratory reference compound intended strictly for in-vitro and laboratory research use only.
Is ezPeps PT-141 intended for human use?+
No. All ezPeps products are sold strictly for laboratory and research use only. They are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
What purity is ezPeps PT-141, and how is it verified?+
Every batch is analyzed by third-party HPLC and confirmed to 99%+ verified purity. A batch-specific Certificate of Analysis (COA) is available in our COA Library so you can review the results for the exact lot you receive.
What form does it ship in, and how should it be stored?+
It ships as a lyophilized (freeze-dried) powder in a sealed vial. Store vials in a cool, dark place; refrigeration or freezing is recommended for long-term storage. Handle according to standard laboratory protocols.
How quickly does ezPeps ship?+
Orders placed before our daily cutoff ship the same day, with domestic US delivery. Every order includes tracking.
Does ezPeps provide a Certificate of Analysis?+
Yes. Each product is backed by a third-party COA accessible through our COA Library and via the QR code on the product, so purity and identity are independently documented.
What is your guarantee?+
ezPeps offers a 30-day money-back guarantee. See our Return and Refund Policy for full details, or contact our support team if you are not satisfied.
New to sourcing research materials? Read our guide: How to Choose a Research Peptide Supplier (and How to Read a COA).
