Description
TESAMORELIN + IPAMORELIN BLEND
For Research Use Only | Not for Human or Veterinary Use
Description:
The Tesamorelin + Ipamorelin Blend combines two complementary growth hormone secretagogue peptides studied together for their converging action on the GH axis. Tesamorelin is a stabilized 44-amino acid GHRH analogue, modified with a trans-3-hexenoic acid group that confers resistance to DPP-IV degradation and stimulates growth hormone release through the GHRH receptor. Ipamorelin is a selective pentapeptide ghrelin receptor agonist that promotes GH secretion without significantly affecting cortisol or prolactin levels. Together they are investigated for sustained, pulsatile GH release through two distinct receptor pathways in preclinical research models.
Scientific Specifications:
- Blend Components: Tesamorelin + Ipamorelin
- Type: Dual Peptide Blend (Modified GHRH Analogue + Selective GH Secretagogue)
- Sequences:
Tesamorelin: (trans-3-hexenoic acid)-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂ (44aa)
Ipamorelin: Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (5aa) - Molecular Formulas: C₂₂₁H₃₆₆N₇₂O₆₇S (Tesamorelin) + C₃₈H₄₉N₉O₅ (Ipamorelin)
- Molecular Weights: ~5135.86 g/mol (Tesamorelin) + ~711.9 g/mol (Ipamorelin)
- CAS Numbers: 218949-48-5 (Tesamorelin) / 170851-70-4 (Ipamorelin)
- PubChem CIDs: 16137828 (Tesamorelin) / 9831659 (Ipamorelin)
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
The Tesamorelin + Ipamorelin Blend is commonly studied for its potential effects on:
- Dual-pathway growth hormone release via GHRH receptor and ghrelin receptor co-activation
- Visceral adipose tissue metabolism and GH-dependent lipolytic pathway activation
- IGF-1 axis regulation and downstream somatomedin-mediated signaling
- Selective GH secretion without significant cortisol or prolactin elevation (Ipamorelin)
- DPP-IV resistance and the pharmacokinetic stability of modified GHRH analogues
- Body composition modulation, recovery, and sleep architecture in preclinical models
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
