Description
MELANOTAN 2
For Research Use Only | Not for Human or Veterinary Use
Description:
Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), originally developed at the University of Arizona. In preclinical laboratory research, Melanotan II has been extensively investigated for its activity at melanocortin receptors (MC1R through MC5R), with particular affinity for MC1R, MC3R, MC4R, and MC5R. The compound’s cyclic lactam structure confers enhanced metabolic stability compared to the linear endogenous ligand, making it a widely used pharmacological tool in melanocortin signaling research, pigmentation biology, and studies of energy homeostasis and sexual function pathways.
Scientific Specifications:
- Peptide Name: Melanotan II (MT-II)
- Type: Synthetic Cyclic Heptapeptide (α-MSH Analogue)
- Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
- Molecular Formula: C₅₀H₆₉N₁₅O₉
- Molecular Weight: 1024.18 g/mol
- CAS Number: 121062-08-6
- PubChem CID: 92432
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
Melanotan II is commonly studied for its potential effects on:
- Melanocortin receptor (MC1R–MC5R) binding affinity and downstream signaling cascades
- Melanogenesis induction and eumelanin production in melanocyte models
- MC4R-mediated regulation of energy homeostasis and appetite signaling pathways
- Sexual function-related neuroendocrine pathways via hypothalamic melanocortin activation
- Photoprotective mechanisms and UV-induced DNA damage response in skin biology models
- Cyclic peptide structure-activity relationships in melanocortin receptor pharmacology
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
What is Melanotan 2?+
Melanotan 2 is a synthetic peptide (a cyclic peptide). ezPeps supplies it as a laboratory reference compound intended strictly for in-vitro and laboratory research use only.
Is ezPeps Melanotan 2 intended for human use?+
No. All ezPeps products are sold strictly for laboratory and research use only. They are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
What purity is ezPeps Melanotan 2, and how is it verified?+
Every batch is analyzed by third-party HPLC and confirmed to 99%+ verified purity. A batch-specific Certificate of Analysis (COA) is available in our COA Library so you can review the results for the exact lot you receive.
What form does it ship in, and how should it be stored?+
It ships as a lyophilized (freeze-dried) powder in a sealed vial. Store vials in a cool, dark place; refrigeration or freezing is recommended for long-term storage. Handle according to standard laboratory protocols.
How quickly does ezPeps ship?+
Orders placed before our daily cutoff ship the same day, with domestic US delivery. Every order includes tracking.
Does ezPeps provide a Certificate of Analysis?+
Yes. Each product is backed by a third-party COA accessible through our COA Library and via the QR code on the product, so purity and identity are independently documented.
What is your guarantee?+
ezPeps offers a 30-day money-back guarantee. See our Return and Refund Policy for full details, or contact our support team if you are not satisfied.
New to sourcing research materials? Read our guide: How to Choose a Research Peptide Supplier (and How to Read a COA).








