Description
MELANOTAN I
For Research Use Only | Not for Human or Veterinary Use
Description:
Melanotan I (afamelanotide) is a synthetic linear tridecapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), developed as a superpotent and enzymatically stable MC1R agonist. In preclinical laboratory research, Melanotan I has been investigated for its high selectivity at the melanocortin 1 receptor (MC1R) and its role in melanogenesis stimulation, eumelanin biosynthesis, and photoprotective signaling pathways. The [Nle⁴, D-Phe⁷] substitutions in the native α-MSH backbone confer significantly enhanced receptor binding affinity and resistance to enzymatic degradation, making it a key research tool in pigmentation biology and melanocortin receptor pharmacology.
Scientific Specifications:
- Peptide Name: Melanotan I (Afamelanotide)
- Type: Synthetic Linear Tridecapeptide (α-MSH Analogue)
- Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
- Molecular Formula: C₇₈H₁₁₁N₂₁O₁₉
- Molecular Weight: ~1646.85 g/mol
- CAS Number: 75921-69-6
- PubChem CID: 16155012
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
Melanotan I is commonly studied for its potential effects on:
- MC1R-selective agonism and melanocortin receptor binding kinetics
- Eumelanin biosynthesis and melanogenesis induction in melanocyte cultures
- UV-induced DNA damage protection and photoprotective signaling mechanisms
- Tyrosinase activity modulation and melanin biosynthetic pathway regulation
- Structure-activity relationships of [Nle⁴, D-Phe⁷]-substituted α-MSH analogues
- Skin pigmentation biology and keratinocyte-melanocyte paracrine interactions
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
What is Melanotan I?+
Melanotan I is a synthetic peptide. ezPeps supplies it as a laboratory reference compound intended strictly for in-vitro and laboratory research use only.
Is ezPeps Melanotan I intended for human use?+
No. All ezPeps products are sold strictly for laboratory and research use only. They are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
What purity is ezPeps Melanotan I, and how is it verified?+
Every batch is analyzed by third-party HPLC and confirmed to 99%+ verified purity. A batch-specific Certificate of Analysis (COA) is available in our COA Library so you can review the results for the exact lot you receive.
What form does it ship in, and how should it be stored?+
It ships as a lyophilized (freeze-dried) powder in a sealed vial. Store vials in a cool, dark place; refrigeration or freezing is recommended for long-term storage. Handle according to standard laboratory protocols.
How quickly does ezPeps ship?+
Orders placed before our daily cutoff ship the same day, with domestic US delivery. Every order includes tracking.
Does ezPeps provide a Certificate of Analysis?+
Yes. Each product is backed by a third-party COA accessible through our COA Library and via the QR code on the product, so purity and identity are independently documented.
What is your guarantee?+
ezPeps offers a 30-day money-back guarantee. See our Return and Refund Policy for full details, or contact our support team if you are not satisfied.
New to sourcing research materials? Read our guide: How to Choose a Research Peptide Supplier (and How to Read a COA).
