Description
SS-31
For Research Use Only | Not for Human or Veterinary Use
Description:
SS-31 (Elamipretide, MTP-131) is a synthetic mitochondria-targeted tetrapeptide that selectively binds to cardiolipin, a phospholipid uniquely concentrated in the inner mitochondrial membrane. In preclinical laboratory research, SS-31 is investigated for its ability to penetrate cell membranes and concentrate at the mitochondrial inner membrane, where it stabilizes cardiolipin-cytochrome c interactions and optimizes electron transport chain function. The peptide’s alternating aromatic-cationic motif (D-Arg-Dmt-Lys-Phe, where Dmt = 2′,6′-dimethyltyrosine) enables cell-permeable, mitochondria-selective accumulation independent of mitochondrial membrane potential, making it a key research tool in mitochondrial medicine, bioenergetics, and oxidative stress biology.
Scientific Specifications:
- Peptide Name: SS-31 (Elamipretide / MTP-131)
- Type: Synthetic Mitochondria-Targeted Tetrapeptide
- Sequence: D-Arg-Dmt-Lys-Phe-NH₂ (Dmt = 2′,6′-dimethyltyrosine)
- Molecular Formula: C₃₂H₄₉N₉O₅
- Molecular Weight: 639.79 g/mol
- CAS Number: 736992-21-5
- PubChem CID: 11764719
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
SS-31 is commonly studied for its potential effects on:
- Cardiolipin stabilization and cytochrome c electron transfer optimization
- Mitochondrial electron transport chain efficiency and ATP production enhancement
- Reactive oxygen species (ROS) generation reduction at complex I and III
- Mitochondrial membrane potential preservation under ischemia-reperfusion conditions
- Age-related mitochondrial dysfunction and cellular bioenergetic decline models
- Cardiolipin peroxidation prevention and mitochondrial cristae structural integrity
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
What is SS-31?+
SS-31 is a synthetic peptide (a tetrapeptide). ezPeps supplies it as a laboratory reference compound intended strictly for in-vitro and laboratory research use only.
Is ezPeps SS-31 intended for human use?+
No. All ezPeps products are sold strictly for laboratory and research use only. They are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
What purity is ezPeps SS-31, and how is it verified?+
Every batch is analyzed by third-party HPLC and confirmed to 99%+ verified purity. A batch-specific Certificate of Analysis (COA) is available in our COA Library so you can review the results for the exact lot you receive.
What form does it ship in, and how should it be stored?+
It ships as a lyophilized (freeze-dried) powder in a sealed vial. Store vials in a cool, dark place; refrigeration or freezing is recommended for long-term storage. Handle according to standard laboratory protocols.
How quickly does ezPeps ship?+
Orders placed before our daily cutoff ship the same day, with domestic US delivery. Every order includes tracking.
Does ezPeps provide a Certificate of Analysis?+
Yes. Each product is backed by a third-party COA accessible through our COA Library and via the QR code on the product, so purity and identity are independently documented.
What is your guarantee?+
ezPeps offers a 30-day money-back guarantee. See our Return and Refund Policy for full details, or contact our support team if you are not satisfied.
New to sourcing research materials? Read our guide: How to Choose a Research Peptide Supplier (and How to Read a COA).
