Description
THYMOSIN ALPHA-1
For Research Use Only | Not for Human or Veterinary Use
Description:
Thymosin Alpha-1 (Tα1, Thymalfasin) is a synthetic 28-amino acid peptide corresponding to the naturally occurring thymic peptide derived from proteolytic cleavage of prothymosin alpha. In preclinical laboratory research, Thymosin Alpha-1 is extensively investigated for its immunomodulatory properties, including enhancement of T-cell maturation, dendritic cell activation, and toll-like receptor (TLR) signaling. The N-terminally acetylated peptide is produced endogenously in thymic epithelial cells and is released during T-cell development, making it a central research tool in immunology, infectious disease biology, and immune checkpoint modulation studies.
Scientific Specifications:
- Peptide Name: Thymosin Alpha-1 (Tα1 / Thymalfasin)
- Type: Synthetic 28-Amino Acid Immunomodulatory Peptide
- Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
- Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅
- Molecular Weight: 3108.3 g/mol
- CAS Number: 62304-98-7
- PubChem CID: 16130571
- Form: Lyophilized powder
- Storage: Store dry in a cool, dark environment (2°C to 8°C)
Research Context:
Thymosin Alpha-1 is commonly studied for its potential effects on:
- T-cell differentiation, maturation, and CD4+/CD8+ subset modulation in thymic models
- Dendritic cell activation and antigen presentation efficiency via TLR9 signaling
- Toll-like receptor (TLR2, TLR9) agonism and innate immune response amplification
- Natural killer (NK) cell cytotoxicity enhancement and immunosurveillance pathways
- Immune checkpoint interactions and T-cell exhaustion reversal in chronic infection models
- Prothymosin alpha processing and thymic peptide biology in immune ontogeny research
Intended Use:
This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.
Legal Disclaimer:
The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale:
By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.
What is Thymosin Alpha-1?+
Thymosin Alpha-1 is a synthetic peptide (a 28-amino-acid peptide). ezPeps supplies it as a laboratory reference compound intended strictly for in-vitro and laboratory research use only.
Is ezPeps Thymosin Alpha-1 intended for human use?+
No. All ezPeps products are sold strictly for laboratory and research use only. They are not intended for human or veterinary use, consumption, or any clinical or diagnostic application.
What purity is ezPeps Thymosin Alpha-1, and how is it verified?+
Every batch is analyzed by third-party HPLC and confirmed to 99%+ verified purity. A batch-specific Certificate of Analysis (COA) is available in our COA Library so you can review the results for the exact lot you receive.
What form does it ship in, and how should it be stored?+
It ships as a lyophilized (freeze-dried) powder in a sealed vial. Store vials in a cool, dark place; refrigeration or freezing is recommended for long-term storage. Handle according to standard laboratory protocols.
How quickly does ezPeps ship?+
Orders placed before our daily cutoff ship the same day, with domestic US delivery. Every order includes tracking.
Does ezPeps provide a Certificate of Analysis?+
Yes. Each product is backed by a third-party COA accessible through our COA Library and via the QR code on the product, so purity and identity are independently documented.
What is your guarantee?+
ezPeps offers a 30-day money-back guarantee. See our Return and Refund Policy for full details, or contact our support team if you are not satisfied.
New to sourcing research materials? Read our guide: How to Choose a Research Peptide Supplier (and How to Read a COA).
